DNA Profiling Malaysia

Genetic testing Gives You the Chance to MODIFY Your Lifestyle to avoid Becoming Sick

"A particular genetic mutation or variance and many sickness develop from external environmental pollution and high-risk genes could be identified. Having the knowledge of you are carrying some high-risk genes might enable you to manage your health risk."

DNA Profiling analyses 54 sets of the most potent genes grouped according to the primary physiological effect they have on your body. It identifies any ‘potential’ genetic variations that may influence the way your body functions and how it responses to how you live your daily life, how you workout and what you consume.

How Can You Benefit from DNA Profiling?


The ‘MULTI-DISCIPLINARY’ Convergence Approach to Healthy Living Healthy Aging

What is DNA Profiling?

DNA profile (DNA fingerprinting) is a term that scientist use for a collection of specific data derived from DNA. Those specific areas of DNA called variable number tandem repeats (VNTR). Scientists developed methods of analysis that uncover the unique nucleotide sequence of VNTRs to use for the personal identification. That data can be used for criminal and forensic investigations, parentage testing, identification of hidden hereditary abnormalities and many other purposes.  It is known that 99.9% of DNA is identical among people. There are some small variations in DNA sequence that give us all that variety of traits that make us different. Those variations used for creating individual genetic passport or profile. Given advancement in the technology the results of DNA profiling are very reliable.

Increasingly DNA profiling or the technique of identifying an individual through the DNA characteristics is being used to understand and interpret the widespread variations amongst the humans and the many complication that arises essentially because of the way these genes are encoded.

Increases Health Awareness
Early Intervention
Healthy Lifestyle

Why Is DNA Profiling Required?


Identify Risks Preventive Measures Targeted Treatment
The information passed on through your genes is important as this could be used to identify if you are at risk for a specific disease or if the alterations if any could affect your life in any significant manner. Tests done for diseases like Down’s syndrome or other genetically transferred diseases look for potential changes in the individual’s gene coding or DNA or the proteins that it is composed of. The whole idea of it is more towards preventive measures. This is useful especially if you are an otherwise healthy person and do not have any specific hereditary issues. There is no way to know what alterations should be looked at. In that context, genetic profiling comes in really handy. On the basis of your DNA profiling, your gene practitioner will be in a position to help you with potential preventive measures and strategies that could have significant long-term impact on both you and your family’s health. The best part about DNA profiling is any preventive measure that would be suggested to you, would be evidence based and not mere assumption and, as a result, the hit rate is way higher.

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It starts with the collection of a DNA sample from almost any biological tissue or fluid. Then, DNA is extracted, purified and analyzed using one of the following methods.

RFLP (restriction fragment length polymorphism) analysis employs gel electrophoresis to separate marked fragments of DNA and further compare and identify their nucleotide sequence. It is an extremely time-consuming method that requires a large amount of high-quality DNA and often is not free from a human error.

PCR (polymerase chain reaction) analysis is faster, but, unfortunately, is more sensitive to the contamination and shows false results in case of a mixed sample.

Latest methods of STR analysis and AmpFLP combine the advantages of previous methods and minimize the downsides. Particular short repeated sequences separated by the gel electrophoresis and amplified using PCR. Sequencing techniques help to identify the nucleotide composition.
Mitochondrial DNA analysis is useful for the highly decayed samples.

In criminal and forensic investigations, the DNA profile of the suspect compared to the DNA profile of the sample obtained at the crime scene. Archaeological and paleontological research often use evidence based on DNA profile.

Medical practitioners benefit from DNA profiling by using it for diagnostics and treatment optimization. This technique widely used for the parental identification and ancestry search.

DNA technologies and particularly the DNA profiling have a controversial public resonance. DNA profiling pros and cons are actively discussed in the scientific circles and mass media.

Some people concerned by the ease of access to their private information because the sample of spit or hair is enough to create a DNA profile. Others point out that one out of hundred DNA profiles contains mistakes, despite the advancement in the technology.

Among the disadvantages of DNA profiling is the sensitivity to the smallest contamination of the sample that may lead to the false results. However, DNA profile analysis actively serves the forensic science and assists in the parentage and ancestry testing. Advantages of this method include non-invasive sample collection and the possibility to create databases for the variety of applications.

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